Glucaric acid is naturally produced by the body and can be taken in by eating fruits and vegetables. Supplemental glucaric acid is formed by adding calcium to produce calcium D-glucarate. It is a detoxifying agent that works to increase liver processes that neutralize harmful chemicals and metabolic byproducts. Preliminary studies have been done on calcium D-glucarate for cancers of the breast, prostate and colon.
Calcium D-glucarate has been shown to decrease enzymes that are thought to stimulate cancer growth. It also helps with hormonally related cancers by decreasing the resorption of estrogen from the gastrointestinal tract. Calcium D-glucarate may also be of benefit for individuals with high cholesterol by decreasing the resorption of cholesterol from the bile, as it travels through the intestines. Interestingly animal models have shown that calcium D-glucarate can decrease kidney damage that is caused by antibiotic use. Calcium D-glucarate may be a beneficial treatment for cancer, high cholesterol and drug induced kidney damage.
Glucaric acid is a nutrient found in many fruits and vegetables. Supplemental glucaric acid is bound to calcium for stability. It is available in capsule or tablet form. Use of calcium D-glucarate in pregnancy and lactation has not been studied. There are no reported side effects for calcium D-glucarate. Calcium D-glucarate may interact with drugs such as diflunisal, ketoprofen, lorazepam, and morphine that are processed by the same set of enzymes in the liver. Alcohol may decrease the effectiveness of this supplement.
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